Publikationen

Pilgram O, Keils A, Benary GE, Müller J, Merkl S, Ngaha S, Huber S, Chevillard F, Harbig A, Magdolen V, Heine A, Böttcher-Friebertshäuser E, Steinmetzer T (2022) Improving the selectivity of 3-amidinophenylalanine-derived matriptase inhibitors. Eur J Med Chem, https://doi.org/10.1016/j.ejmech.2022.114437.

Huber S, Braun NJ, Schmacke LC, Quek JP, Murra R, Bender D, Hildt E, Luo D, Heine A, Steinmetzer T (2022) Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. J Med  Chem, https://doi.org/10.1021/acs.jmedchem.1c01860.

Prakash PS, Weber MHW, Hellemond JJ, Falcone FH (2021) Are humanized IgE reporter systems potential game changers in serological diagnosis of human parasitic infection? Parasitol Res, https://doi.org/10.1007/s00436-021-07352-z.

Gallinger TL, Aboagye SY, Obermann W, Weiss M, Grünweller A, Unverzagt C, Williams DL, Schlitzer M, Haeberlein S. (2022) First In Silico Screening of Insect Molecules for Identification of Novel Anti-Parasitic Compounds. Pharmaceuticals 15(2):119, https://doi: 10.3390/ph15020119.

Obermann W, Friedrich A, Madhugiri R, Klemm P, Mengel JP, Hain T, Pleschka S, Wendel HG, Hartmann RK, Schiffmann S, Ziebuhr J, Müller C, Grünweller A (2022) Rocaglates as Antivirals: Comparing the Effects on Viral Resistance, Anti-Coronaviral Activity, RNA-Clamping on eIF4A and Immune Cell Toxicity. Viruses 14(3):519, https://doi: 10.3390/v14030519.

Roser LA, Erkoc P, Ingelfinger R, Henke M, Ulshofer T, Schneider AK, Laux V, Geisslinger G, Schmitt I, Fürst R, Schiffmann S (2022) Lecanoric acid mediates anti-proliferative effects by an M phase arrest in colon cancer cells. Biomed Pharmacother 148, 112734, https://doi.org/10.1016/j.biopha.2022.112734.

de Bruin N, Schneider AK, Reus P, Talmon S, Ciesek S, Bojkova D, Cinatl J, Lodhi I, Charlesworth B, Sinclair S, Pennick G, Laughey WF, Gribbon P, Kannt A, Schiffmann S (2022) Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In Vitro SARS-CoV-2 Infection. Int J Mol Sci 23, 1049, https://doi.org/ 10.3390/ijms23031049.

Murangi T, Prakash P, Pereira Moreira B, Basera W, Botha M, Cunningham S, Facey-Thomas H, Halajian A, Joshi L, Ramjith J, Falcone FH, Hrsnell W, Levin ME (2022) Ascaris lumbricoides and ticks associated with sensitization to galactose α1,3-galactose and elicitation of the alpha-gal syndrome. J Allergy Clin Immunol, https://doi.org/10.1016/j.jaci.2021.07.018.

Herrlein M, Schmanke P, Elgner F, Sabino C, Akhras S, Bender D, Glitscher M, Tabari D, Scholl C, Stingl J, Hildt E (2022) Catch Me if You Can: the Crosstalk of Zika virus and the Restriction Factor Tetherin. J Virol, https://doi.org/10.1128/jvi.02117-21.

Fritz-Wolf K, Bathke J, Rahlfs S, Becker K (2022) Crystal structure of plasmoredoxin, a redox-active protein unique for malaria parasites. CRSB, https://doi.org/10.1016/j.crstbi.2022.03.004.

Wiedemann KR, Peter Ventura A, Gerbig S, Roderfeld M, Quack T, Grevelding CG, Roeb E, Spengler B (2022) Changes in the lipid profle of hamster liver after Schistosoma mansoni infection, characterized by mass spectrometry imaging and LC–MS/MS analysis. Anal Bioanal Chem, https://doi.org/10.1007/s00216-022-04006-6.

Moreira BP, Weber MHW, Haeberlein S, Mokosch AS, Spengler B, Grevelding CG, Falcone FH (2022) Drug Repurposing and De Novo Drug Discovery of Protein Kinase Inhibitors as New Drugs against Schistosomiasis. Molecules 27, 1414, https://doi.org/10.3390/molecules27041414.

Dekevic G, Tasto L, Czermak P, Salzig D (2022) Statistical experimental designs to optimize the transient transfection of HEK 293T cells and determine a transfer criterion from adherent cells to larger-scale cell suspension cultures. J Biotechnol, https://doi.org/10.1016/j.jbiotec.2022.01.004.

Morawietz CM, Peter Ventura AM, Grevelding CG, Haeberlein S, Spengler B (2022) Spatial visualization of drug uptake and distribution in Fasciola hepatica using high‑resolution AP‑SMALDI mass spectrometry imaging. Parasitol Res 121:1145–1153, https://doi.org/10.1007/s00436-021-07388-1.

Coburn J, Garcia B, Hu LT, Jewett MW, Kraiczy P, Norris SJ, Skare J (2021) Lyme Disease Pathogenesis. Mol. Biol. Vol. 42, DOI: https://doi.org/10.21775/cimb.042.473.

Leister H, Luu M, Staudenraus D, Lopez Krol A, Mollenkopf HJ, Sharma A, Schmerer N, Schulte LN, Bertrams W, Schmeck B, Bosmann M, Steinhoff U, Visekruna A (2021) Pro- and anti-tumorigenic capacity of immunoproteasomes in shaping the tumor microenvironment. Cancer Immunol Res, 2021 June; 9(6): 682–692, doi:10.1158/2326-6066.CIR-20-0492.

Stukalov A, Girault V, Grass V, Karayel O, Bergant V, Urban C, Haas DA, Huang Y, Oubraham L, Wang A, Hamad MS, Piras A, Hansen FM, Tanzer MC, Paron I, Zinzula L, Engleitner T, Reinecke M, Lavacca TM, Ehmann R, Wölfel R, Jores J, Kuster B, Protzer U, Rad R, Ziebuhr J, Thiel V, Scaturro P, Mann M, Pichlmair A (2021) Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Nature 594(7862):246-252. doi: 10.1038/s41586-021-03493-4.

Slanina H, Madhugiri R, Bylapudi G, Schultheiß K, Karl N, Gulyaeva A, Gorbalenya AE, Linne U, Ziebuhr J (2021) oronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit. Proc Natl Acad Sci, 118(6)e2022310118, doi: 10.1073/pnas.2022310118.

Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C (2021) Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes. Sci Adv 7(10):eabf1004, doi: 10.1126/sciadv.abf1004.

Mughal MN, Grevelding CG, Haeberlein S (2021) First insights into the autophagy machinery of adult Schistosoma mansoni. Int J Parasitol, https://doi.org/10.1016/j.ijpara.2020.11.011.

Schoebel A, Nguyen-Dinh V, Schumann GG, Herker E (2021) Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells. PLoS Pathog 17(4): e1009496. https://doi.org/10.1371/journal.ppat.1009496.

Herker E, Vieyres G,Beller M, Krahmer N, Bohnert M (2021) Lipid Droplet Contact Sites in Health and Disease. Cell Biol (5):345-358, https://doi.org/10.1016/j.tcb.2021.01.004.

Nguyen-Dinh V, Herker E (2021). Ultrastructural Features of Membranous Replication Organelles Induced by Positive-Stranded RNA Viruses. Cells 10 (9), 2407, http://dx.doi.org/10.3390/cells10092407.

Peter Ventura AM, Haeberlein S, Konopka L, Obermann W, Grünweller A, Grevelding CG, Schlitzer M (2021) Synthesis and antischistosomal activity of linker- and thiophene-modified biaryl alkyl carboxylic acid derivatives. Arch Pharm, https://doi.org/10.1002/ardp.202100259.

Dichter A, Schultze TG, Wenigmann A, Ballhorn W, Latz A, Schlüfter E, Ventosilla P, Guerra Allison H, Ugarte-Gil C, Tsukayama P, Kempf VAJ (2021) Identification of immunodominant Bartonella bacilliformis proteins: a combined in-silico and serology approach. Lancet Microbe, https://doi.org/10.1016/S2666-5247(21)00184-1.

Halwe S, Kupke A, Vanshylla K, Liberta F, Gruell H, Zehner M, Rohde C, Krähling V, Gellhorn Serra M, Kreer C, Klüver M, Sauerhering L, Schmidt J, Cai Z, Han F, Yound D, Yang G, Widera M, Koch M, Werner AD, Kämpfer L, Becker N, Marlow MS, Eickmann M, Ciesek S, Schiele F, Klein F, Becker S (2021) Interanasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection. Viruses https://doi.org/10.3390/V13081498.

Vélez J, Silva LMR, Kamena F,  Daugschies A,  Mazurek S,  Taubert A,  Hermosilla C (2022) The Oesophageal Squamous Cell Carcinoma Cell Line COLO-680N Fails to Support Sustained Cryptosporidium parvum Proliferation. Pathogens, 11, 49. https://doi:10.3390/pathogens11010049.Mughal MN, Grevelding CG, Haeberlein S (2021) The anticancer drug imatinib induces autophagy in Schistosoma mansoni. Int J Parasitol 52(4):211-215, DOI: 10.1016/j.ijpara.2021.10.008 .

Vélez J, Silva LMR, Gärtner U, Daugschies A, Mazurek S, Hermosilla C, Taubert A (2021) First Metabolic Insights into Ex Vivo Cryptosporidium parvum-Infected Bovine Small Intestinal Explants Studied under Physioxic Conditions. Biology 10, 963, https://doi.org/10.3390/biology10100963.

Vélez J, Velasquez Z, Silva LMR, Gärtner U, Failing K, Daugschies A , Mazurek S, Hermosilla C, Taubert A (2021) Metabolic Signatures of Cryptosporidium parvum-Infected HCT-8 Cells and Impact of Selected Metabolic Inhibitors on C. parvum Infection under Physioxia and Hyperoxia. Biology 10, 60, https://doi.org/10.3390/biology10010060.

Dahms SO, Haider T, Klebe G, Steinmetzer T, Brandstetter H (2021) OFF-State-Specific Inhibition of Convertase Furin. ACS Chem. Biol. 2021, 16, 1692−1700, https://doi.org/10.1021/acschembio.1c00411

Paraskevopoulou V, Schimpl M, Overman RC, Stolnik S, Chen Y, Nguyen L, Winkler GS, Gellert P, Klassen JS, Falcone FH (2021) Structural and binding characterization of the LacdiNAc-specific adhesin (LabA; HopD) exodomain from Helicobacter pylori. Curr Res Struct Biol, https://doi.org/10.1016/j.crstbi.2020.12.004.

von Bülow V, Lichtenberger J, Grevelding CG , Falcone FH , Roeb E, Roderfeld M (2021) Does Schistosoma Mansoni Facilitate Carcinogenesis? Cells 10 1982, https://doi.org/10.3390/cells10081982.

Basic M, Kubesch A, Kuhnhenn L, Görgülü E, Finkelmeier F, Dietz J, Knabe M, Mücke VT, Mücke MM,  Berger A, Zeuzem S, Sarrazin C, Hildt E, Peiffer KH (2021) Not uncommon: HBV genotype G co-infections among healthy European HBV carriers with genotype A and E infection. Liver Int, https://doi.org/10.1111/liv.14884.

Glitscher M, Hildt E (2021) Endosomal Cholesterol in Viral Infections – A Common Denominator? Front Physiol, https://doi.org/10.3389/fphys.2021.750544.

Glischer M, Hildt E (2021) Hepatitis E virus egress and beyond – the manifold roles of the viral ORF3 protein. Cell Microbio, https://doi.org/ https://doi.org/10.1111/cmi.13379.

Han N, Hwang W, Tzelepis K, Schmerer P, Yankova E, MacMahon M, Lei W, Katritsis MN, Liu A,  Felgenhauer U, Schuldt A, Harris R, Chapman K, McCaughan F, Weber F, Kouzarides T(2021) Identification of SARS-CoV-2–induced pathways reveals drug repurposing strategies. Sci Adv, https:doi.org/10.1126/sciadv.abh3032.

Basic M, Kubesch A, Kuhnhenn L, Görgülü E, Finkelmeier F, Dietz J, Knabe M, Mücke VT, Mücke MM, Berger A, Zeuzem S, Sarrazin C, Hildt E, Peiffer KH (2021) Not uncommon: HBV genotype G co-infections among healthy European HBV carriers with genotype A and E infection. Liver International, https://doi.org/10.1111/liv.14884.

Peter Ventura AM, Haeberlein S, Konopka L, Obermann W, Grünweller A, Grevelding CG, Schlitzer M (2021) Synthesis and antischistosomal activity of linker- and thiophene-modified biaryl alkyl carboxylic acid derivatives. Arch Pharm, https://doi.org/10.1002/ardp.202100259.

Kirstgen M, Müller SF, Lojaga, KAAT, Goldmann N, Lehmann F, Alakurtti S, Yli-Kauhaluoma J, Baringhaus K-H, Krieg R, Glebe D, Geyer J (2021) Identification of Novel HBV/HDV Entry Inhibitors by Pharmacophore- and QSAR-Guided Virtual Screeing. Viruses, 13(8), 1489; https://doi.org/10.3390/v13081489.

Harnischfeger J, Beutler M, Salzig D, Rahlfs S, Becker K, Grevelding CG, Czermak P (2021) Biochemical characterization of the recombinant schistosome tegumental protein SmALDH_312 produced in E. coli and baculovirus expression vector system. Electron J Biotechnol, https://doi.org/10.1016/j.ejbt.2021.08.002.

Sabino C, Bender D, Herrlein ML, Hildt E (2021) The epidermal growth factor receptor is a relevant host factor in the early stage of Zika virus life cycle in vitro. J Virol, doi: 10.1128/JVI.01195-21.

Kirstgen M, Lowjaga KAAT, Müller SF, Goldmann N, Lehmann F, Glebe D, Baringhaus KH, Geyer J (2021) Hepatitis D Virus Entry Inhibitors Based on Repurposing Intestinal Bile Acid Reabsorption Inhibitors. Viruses 13, 666. https://doi.org/10.3390/v13040666.

Eilts F, Harnischfeger J, Loewe D, Wolff M, Salzig D, Czermak P (2021) Production of baculovirus and stem cells for baculovirus-mediated gene transfer into human mesenchymal stem cells. Methods Mol Biol, 2183:367-390, doi: 10.1007/978-1-0716-0795-4_19.

Lothert K, Dekevic G, Loewe D, Salzig D, Czermak P, Wolff MW (2021) Production of baculovirus and stem cells for baculovirus-mediated gene transfer into human mesenchymal stem cells. Methods Mol Biol, 2183:217-248, doi: 10.1007/978-1-0716-0795-4_12.

Müller MA, Kompauer M, Strupat K, Heiles S, Spengler B (2021) Implementation of a high-repetition-rate laser in an AP-SMALDI MSI system for enhanced measurement performance, J Am Soc Mass Spectrom, 32(2):465-472. doi: 10.1021/jasms.0c00368.

Ghezellou P, Heiles S, Kadesch P, Ghassempour A, Spengler B (2021) Venom Gland Mass Spectrometry Imaging of Saw-Scaled Viper, Echis carinatus sochureki, at High Lateral Resolution, J Am Soc Mass Spectrom, doi: 10.1021/jasms.1c00042.

Mokosch A, Gerbig S, Grevelding CGHaeberlein SSpengler B (2021) High-resolution AP-SMALDI MSI as a tool for drug imaging in Schistosoma mansoni. Anal Bioanal Chemhttps://doi.org/10.1007/s00216-021-03230-w.

Taroncher-Oldenburg G, Müller C, Obermann W, Ziebuhr J, Hartmann RK, Grünweller A (2021) Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates – A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics. Microorganisms 9https://doi.org/10.3390/microorganisms9030540.

Frese N, Schmerer P, Wortmann M, Schürmann M, König M, Westphal M, Weber F, Sudhoff H, Gölzhäuser A (2021) Imaging of SARS-CoV-2 infected Vero E6 cells by helium ion microscopy. Beilstein J Nanotechnology, https://doi.org/10.3762/bjnano.12.13.

Glitscher M, Martín DH, Woytinek K, Schmidt B, Tabari D, Scholl C, Stingl JC, Seelow E, Choi M, Hildt E (2021) Targeting cholesterol metabolism as an efficient antiviral strategy against the hepatitis E virus. Cell Mol Gastroenter, https://doi.org/10.1016/j.jcmgh.2021.02.002.

Lam van TV, Heindl MR, Schlutt C, Böttcher-Friebertshäuser E, Bartenschlager R, Klebe G, Brandstetter H, Dahms SO, Steinmetzer T (2021) The basicity makes the difference – Improved canavanine-derived inhibitors of the proprotein convertase furin. ACS Med Chem Lett, https://doi.org/10.1021/acsmedchemlett.0c00651.

Slanina H, Madhugiri R, Bylapudi G, Schultheiß K, Karl N, Gulyaeva A, Gorbalenya AE, Linne U, Ziebuhr J (2021) Coronavirus replication–transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit. PNAS 118 (6) e2022310118.

Glitscher M, Himmelsbach K, Woytinek K, Schollmeier A, Johne R, Praefcke GJK, Hildt E (2021) Identification of the interferon-inducible GTPase GBP1 as major restriction factor for the Hepatitis E virus. J Viroldoi: 10.1128/JVI.01564-20.

Krähling V, Halwe S, Rohde C, Becker D, Berghöfer S, Dahlke C, Eickmann M, Ercanoglu MS, Gieselmann L, Herwig A, Kupke A, Müller H, Neubauer-Rädel P, Klein F, Keller C, Becker S (2021) Development and characterization of an indirect ELISA to detect SARS-CoV-2 spike protein-specific antibodies. J Immunol Methods, 490, 112958.

Müller C, Obermann W, Karl N, Wendel HG, Taroncher-Oldenburg G, Pleschka S, Hartmann RK, Grünweller AZiebuhr J (2021) The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivoAntiviral Res, 7:105012. doi: 10.1016/j.antiviral.2021.105012.

Pritchard DI, Falcone FH, Mitchell PD (2021) The evolution of IgE-mediated type I hypersensitivity and its immunological value. Allergy, 00: 1– 17. https://doi.org/10.1111/all.14570.

Roderfeld M, Padem M, Lichtenberger J, Quack T, Weiskirchen R, Longerich T, Schramm G, Churin Y, Irungbam K, Tschuschner A, Windhorst A, Grevelding CG, Roeb E (2020) Schistosoma mansoni Egg-Secreted Antigens Activate Hepatocellular Carcinoma-Associated Transcription Factors c-Jun and STAT3 in Hamster and Human Hepatocytes, Hepatology 72(2):626-641, doi: 10.1002/hep.30192.

Schreiner S, Didio A, Hung LH, Bindereif A (2020) Design and application of circular RNAs with protein-sponge function, Nucleic Acids Res 48:12326-12335, doi: 10.1093/nar/gkaa1085.

Tabari D, Scholl C, Steffens M, Weickhardt S, Elgner F, Bender D, Herrlein ML, Sabino C, Semkova V, Peitz M, Till A, Brüstle O, Hildt E, Stingl J (2020) Impact of Zika Virus Infection on Human Neural Stem Cell MicroRNA Signatures, Viruses, 12(11):1219, doi: 10.3390/v12111219.

Mbanefo EC, Agbo CT, Zhao Y, Lamanna OK, Thai KH, Karinshak SE, Khan MA, Fu CL, Odegaard JI, Saltikova IV, Smout MJ, Pennington LF, Nicolls MR, Jardetzky TS, Loukas A, Brindley PJ, Falcone FH, Hsieh MH (2020) IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis, Infect Agent Cancer 15:63, doi: 10.1186/s13027-020-00331-6.

Colella P, Sellier P, Gomez MJ, Biferi MG, Tanniou G, Guerchet N, Cohen-Tannoudji M, Moya-Nilges, van Wittenberghe L, Daniele N, Gjata B, Krijnse-Locker J, Collaud F, Simon-Sola M, Charles S, Cagin U, Mingozzi F (2020) Gene therapy with secreted acid alpha-glucosidase rescues Pompe disease in a novel mouse model with early-onset spinal cord and respiratory defects, EBioMedicine 61:103052, doi: 10.1016/j.ebiom.2020.103052.

Cagin U, Puzzo F, Gomez MJ, Moya-Nilges M, Sellier P, Abad C, van Wittenberghe L, Daniele N, Guerchet N, Gjata B, Collaud F, Charles S, Simon-Sola M, Boyer O, Krijnse-Locker J, Ronzitti G, Colella P, Mingozzi F (2020) Rescue of Advanced Pompe Disease in Mice with Hepatic Expression of Secretable Acid α-Glucosidase, Mol Ther 28(9):2056-2072, doi: 10.1016/j.ymthe.2020.05.025.

Nkamba I, Mulet C, Dubey GP, Gorgette O, Couesnon A, Salles A, Moya-Nilges M, Jung V, Gaboriau-Routhiau V, Guerrera ID, Shima T, Umesaki Y, Nigro G, Krijnse-Locker J, Bérard M, Cerf-Bensussan N, Sansonetti PJ, Schnupf P (2020) Nat Microbiol, 5(1):34-39, doi: 10.1038/s41564-019-0608-1.

Blanco-Rodriguez G, Gazi A, Monel B, Frabetti S, Scoca V, Mueller F, Schwartz O, Krijnse-Locker J, Charneau P, Di Nunzio F (2020) Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes, J Virol 94(11) :e00135-20, doi: 10.1128/JVI.00135-20.

Cagin U, Puzzo F, Gomez MJ, Moya-Nilges M, Sellier P, Abad C, Van Wittenberghe L, Daniele N, Guerchet N, Gjata B, Collaud F, Charles S, Simon-Sola M, Boyer, Krijnse-Locker J, Ronzitti G, Colella P, Mingozzi F (2020) Liver expression of secretable GAA rescues advanced Pompe disease at the biochemical, functional, and transcriptional level in Gaa−/− mice, Mol Genet Metab 129(2):S36-S37.

Morty RE, Ziebuhr J (2020) Call for Papers: The Pathophysiology of COVID-19 and SARS-CoV-2 Infection, Am J Physiol Lung Cell Mol Physiol, 318(5):L1016-L1019, doi: 10.1152/ajplung.00136.2020.

Häcker I, Koller R, Eichner G, Martin J, Liapi E, Rühl J, Rehling T, Schetelig MF (2020) Evaluation of Hydrogen Peroxide Fumigation and Heat Treatment for Standard Emergency Arthropod Inactivation in BSL-3 Insectaries. Front Bioeng Biotechnol, https://doi.org/10.3389/fbioe.2020.602937.

Weglage J, Wolters F, Hehr L, Lichtenberger J, Wulz C, Hempel F, Baier A, Quack T, Köhler K, Longerich T, Schramm G, Irungbam K, Mueller H, von Buelow V, Tschuschner A, Odenthal M, Drebber U, El Arousy M, Ramalho LNZ, Bankov K, Wild P, Pons‑Kühnemann J, Tschammer J, Grevelding CG, Roeb E, Roderfeld M (2020) Schistosoma mansoni eggs induce Wnt/β‑catenin signaling and activate the protooncogene c‑Jun in human and hamster colon. Sci Rep, 10:22373, https://doi.org/10.1038/s41598-020-79450-4.

Blum L, Ulshöfer T, Henke M, Krieg R, Berneburg I, Geisslinger G, Becker K, Parnham MJ, Schiffmann S (2020) The immunomodulatory potential of the arylmethylaminosteroid sc1o. JMolMed, https://doi.org/10.1007/s00109-020-02024-4.

Kirstgen M, Lowjaga KAAT, Müller SF, Goldmann N, Lehmann F, Alakurtti S, Yli-Kauhaluoma J, Glebe D, Geyer J (2020) Selective Hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids. Sci Rep 10:21772, doi: 10.1038/s41598-020-78618-2.

Kadesch P, Gerbig S, Mokosch A, Häberlein S, Spengler B (2020) Parasiten im Massenspektrometer. NadC, https://doi.org/10.1002/nadc.20204093357.

Ghezellou P, Albuquerque W, Garikapati V, Casewell NR, Kazemi SM, Ghassempour A, Spengler B (2020) Integrating top-down and bottom-up mass spectrometric strategies for proteomic profiling of Iranian saw-scaled viper, Echis carinatus sochureki, venom. J Proteome Res, https://dx.doi.org/10.1021/acs.jproteome.0c00687.

Morawietz C M, Houhou H, Puckelwaldt O, Hehr L, Dreisbach D, Mokosch A, Roeb E, Roderfeld M, Spengler B*, Haeberlein S* (2020) Targeting kinases in Fasciola hepatica: anthelminthic effects and tissue distribution of selected kinase inhibitors. Front Vet Sci, doi: 10.3389/fvets.2020.611270.

Kadesch P, Hollubarsch T, Gerbig S, Schneider L, Silva LMR, Hermosilla C, Taubert A, Spengler B (2020) Intracellular parasites Toxoplasma gondii and Besnoitia besnoiti, Unveiled in single host cells using AP-SMALDI MS imaging. J Am Soc Mass Spectrom 31, 1815 – 1824, https://dx.doi.org/10.1021/jasms.0c00043.

Beller M, Herker E, Fullekrug J (2020) Grease on-perspectives in lipid droplet biology. Semin Cell Dev Biol, doi: 10.1016/j.semcdb.2020.06.017.

Bley H, Schobel A, Herker E (2020) Whole lotta lipids-from HCV RNA replication to the mature viral particle. Int J Mol Sci 21, http://dx.doi.org/10.3390/ijms21082888.

Blum L, Gul S, Ulshöfer T, Henke M, Krieg R, Berneburg I, Thomas D, Trautmann S, Kurz J, Geyer J, Geisslinger G, Becker K, Parnham MJ, Schiffmann S (2020) In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o. Sci Rep. 10:7534, doi: 10.1038/s41598-020-64382-w.

Klöss S, Dehmel S, Braun A, Michael JP, Koehl U, Schiffmann S (2020) From cancer to immune-mediated diseases and tolerance induction: Lessons learned from immune oncology and classical anti-cancer treatment. Front Immunol. 11:1423. doi: 10.3389/fimmu.2020.01423.

Peiffer KH, Spengler C, Basic M, Jiang B, Kuhnhenn L, Obermann W,  Zahn T, Glitscher M, Loglio A,  Facchetti F, Carra G, Kubesch A, Vermehren J, Knop V, Graf C, Dietz J, Finkelmeier F, Herrmann E,  Trebicka J, Grünweller A, Zeuzem S, Sarrazin C, Lampertico P, Hildt E (2020) Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers. JCI Insight. 15:135833; doi: 10.1172/jci.insight.135833.

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